International non-launched name: Lemininer.
2. Dosage form: tablets for oral use.
Credelio as a active substance contains a lamp.
The drug is produced in five modifications: Credelio with a lunch content of 56. 25 mg/table. 112. 5 mg/table. 225 mg/table. 450 mg/table. Or 900 mg/table.
As auxiliary substances, the loan contains: cellulose in powder, lactose monohydrate, microcrystalline cellulose, povidon, povidon, sodium lauryl sulfate, silicide-water-water dioxide, magnesium staparate and additive with beef taste.
3. In appearance, Credelio is a round flavored chewing tablets from white to beige with brown spots.
The shelf life of the drug, subject to storage conditions, is 30 months from the date of production.
It is forbidden to use credentials after expiration.
4. Products loaned by 1 or 3 tablets in blisters from aluminum foil.
Each blister is placed in an individual cardboard box and supplied with instructions for use.
5. Store the drug in a closed packaging of the manufacturer, separately from food and feed, in a place protected from light, at a temperature of 0 ° C to 25 ° C.
6. Store in places inaccessible to children.
7. The unused drug is utilized in accordance with the requirements of the law.
8. Vacation conditions: without a prescription of a veterinarian.
Pharmacological properties
9. Credelio refers to systemic-acaricids of systemic action.
10. The drug is active in relation to fleas (CTENOCEPHALIDES FELIS and S. Canis) and ticks (RHIPICEPHALUS SANGUINEUS, Ixodes Ricinus, I. Hexagonus, I. Scapularis, I. Holocyclus, Dermacentor Reticulatus, D. Variabilis and AMBLAMMA AMERIMMA).
Litootelainer is an enantiomer of the Izoxazoline class.
Credelio
The mechanism of action of the lamp is suppressed in the suppression of the dependent channels of the receptors of arthropods, which leads to a violation of the transmission of nerve impulses, paralysis and the death of ticks and fleas.
After the oral administration of the drug, the LOLOLINERN is well absorbed in the gastrointestinal tract, reaching maximum blood plasma concentrations within 2 hours.
The bioavailability of the drug increases in the presence of feed.
The terminal period of the half-life of the launcher is about 4 weeks, which ensures prolonged efficiency of the drug during the entire period between the methods of the drug.
On the animal already infected with fleas, the drug begins to kill parasites within 2 hours after its use, provides their full death for 6 hours and continues to operate within 1 month.
With regard to repeated infestations, the drug provides flea death within 4 hours and continues to operate within a month.
The effect of the drug against ticks begins within 4 hours after its use.
With regard to new infestations with ticks – within 8 hours and continues to operate within 1 month.
The drug provides the death of fleas until the eggs are laying, thereby interrupting the life cycle of fleas.
Litooting is excreted from the body, mainly with bile, renal excretion is a slight way of excretion (less than 10% of the dose).
Litootliner is metabolized to a small extent into hydrophilic compounds, which are observed in feces and urine.
Credelio in terms of exposure to the body relate to moderately dangerous substances (hazard class 3 in accordance with GOST 12. 1. 007).
The procedure for applying a veterinary drug
11. Credelio is prescribed to dogs for the treatment and prevention of arachnia-entomosis, as well as in the complex therapy of allergic dermatitis caused by fleas.
12. Contraindication to use is the increased individual sensitivity of the animal to the components of the drug (including an anamnesis), as well as severe impaired liver and kidney function.
It is not recommended to use loans to puppies younger than 8 weeks and dogs weighing less than 1. 3 kg.
13. When working with the drug Credelio, the general rules of personal hygiene and safety precautions should be followed when working with drugs.
At the end of the work, the hands should be washed with warm water and soap.
People with hypersensitivity to the components of the drug should avoid direct contact with credentials.
An empty packaging from under the drug should be disposed of with household waste.
In the event of allergic reactions or if the drug accidentally gets into the human body, you should immediately contact a medical institution (have instructions for the use of the drug or label with you).
14. Special studies on the use of credentials to pregnant women and lactating bitches were not carried out.
If necessary, the use of the drug is possible under the supervision of a veterinarian, if the expected benefit to the mother outweighs the potential risk to the fetus.
15. The drug is used individually orally once with food or immediately after feeding at a dose of 20 to 43 mg of Lotilaner per 1 kg of animal weight.
Single doses of the drug, depending on the weight of the animal and the type of tablets used, are presented in Table 1.
Table 1
For dogs weighing over 45 kg, use the appropriate combination of tablets.
The drug provides protection against fleas and ticks for 1 month.
If necessary, repeat the treatment after 30 days.
Credelio can be used in the complex therapy of allergic dermatitis caused by fleas.
16. When using Credelio in accordance with the instructions, side effects and complications, as a rule, are not observed.
With increased individual sensitivity and the development of allergic reactions, the use of the drug is stopped and desensitizing therapy is carried out.
17. With an overdose of the drug, there may be a decrease in body weight, depression, piloerection, shortness of breath.
18. There is no information on the incompatibility of the drug with drugs of other pharmacological groups and feed additives.
19. Features of the action of Credelio during its first application and cancellation have not been established.
20. Violation of the drug regimen should be avoided, as this may lead to a decrease in therapeutic efficacy.
In case of skipping the next treatment, it is necessary to resume the use of the drug in the same dose and according to the same scheme.
21. Credelio is not intended for use in productive animals.
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